反応 #74885

反応方程式

6,7-epoxy-2,6,10,10-tetramethyl-1-oxa-spiro[4.5]dec-3-ene

LiAlH4

→

2,6,10,10-tetramethyl-1-oxa-spiro[4.5]dec-3-ene-6-ol

収率 174.2%

反応条件

後処理

1. 1
   洗浄After the usual treatments of washing
2. 2
   その他drying
3. 3
   その他evaporation
4. 4
   workup.DISTILLATIONthe fractional distillation of the obtained residue

実験手順

1.08 g (0.01 M) of 6,7-epoxy-2,6,10,10-tetramethyl-1-oxa-spiro[4.5]dec-3-ene -- see method B, letter i-- were reduced by means of 570 mg (0.015 M) of LiAlH4 in accordance with the above process. After the usual treatments of washing, drying and evaporation, the fractional distillation of the obtained residue gave 1.9 g (ca. 90%) of 2,6,10,10-tetramethyl-1-oxa-spiro[4.5]dec-3-ene-6-ol, b.p. 80°-90°/0.1 Torr.

出典