反応 #74880

反応方程式

stearic acid chloride

sorbitol

hydrochloric acid

→

sorbitol stearate

溶媒

toluene

pyridine

反応条件

後処理

1. 1
   workup.ADDITIONare added dropwise to this mixture over 25 minutes
2. 2
   その他(at approx. 110° C.)
3. 3
   その他for 1 hour
4. 4
   温度under reflux
5. 5
   温度After cooling
6. 6
   洗浄is then washed with water until neutral and
7. 7
   乾燥dried with dehydrated sodium sulphate
8. 8
   その他After concentration of the organic phase the sorbitol stearate crystallizes
9. 9
   その他It is recrystallized from methanol

実験手順

411.5 g (1.358 mols) stearic acid chloride are dissolved in 3 l toluene and heated to 90° C. 41.23 g (0.22 mols) of sorbitol, dissolved in 200 ml pyridine are added dropwise to this mixture over 25 minutes. The solution is boiled (at approx. 110° C.) for 1 hour under reflux. After cooling, dilute hydrochloric acid is added to acidify the mixture, which is then washed with water until neutral and dried with dehydrated sodium sulphate. After concentration of the organic phase the sorbitol stearate crystallizes. It is recrystallized from methanol.

出典