反応 #74716

反応方程式

2-(1-hydroxyethyl)-3-bromo-furan

bromine

water

HCl

→

maltol

溶媒

methanol

反応条件

後処理

1. 1
   その他the reaction
2. 2
   その他to come to room temperature
3. 3
   その他removing much of the methanol
4. 4
   温度After cooling

実験手順

To a sample of 2-(1-hydroxyethyl)-3-bromo-furan (0.54 g, 2.8 mmoles) in 15 ml water and 15 ml methanol at 0° C. was added 0.24 g (3.0 mmoles) of bromine. After allowing the reaction to come to room temperature, the reaction was treated with 3 ml of conc. HCl and heated to 96° C. for 2 hours, removing much of the methanol. After cooling, maltol was isolated by the method of Example 1.

出典