反応 #747091

反応方程式

hydrogen peroxide

3-amino-2-chloro-6-methylphenol hydrochloride

4-(pyrrolidin-1-yl)aniline dihydrochloride

ammonium hydroxide

→

3-amino-2-chloro-6-methyl-4-[(4-pyrrolidin-1-ylphenyl)imino]cyclohexa-2,5-dien-1-one

収率 53.9%

溶媒

water

ethanol

反応条件

後処理

1. 1
   workup.WAITThe mixture is left
2. 2
   その他the precipitate formed
3. 3
   ろ過is filtered off

実験手順

1.94 g of 3-amino-2-chloro-6-methylphenol hydrochloride are added to 2.35 g of 4-(pyrrolidin-1-yl)aniline dihydrochloride in solution in 15 ml of water and 15 ml of ethanol. The pH is adjusted to 9.5 with 20% ammonium hydroxide and then 18 ml of 9% aqueous hydrogen peroxide solution are added. The mixture is left stirring at ambient temperature for 4 hours and then the precipitate formed is filtered off. 1.7 g of 3-amino-2-chloro-6-methyl-4-[(4-pyrrolidin-1-ylphenyl)imino]cyclohexa-2,5-dien-1-one (1m) are thus obtained.

出典