反応 #747089

反応方程式

hydrogen peroxide

3-amino-2-chloro-6-methylphenol hydrochloride

2-[(4-aminophenyl)(ethyl)amino]ethanol hydrochloride

ammonium hydroxide

→

3-amino-2-chloro-4-({4-[ethyl(2-hydroxyethyl)amino]phenyl}imino)-6-methylcyclohexa-2,5-dien-1-one

収率 73.1%

溶媒

water

ethanol

water

反応条件

後処理

1. 1
   ろ過The solid form is filtered off
2. 2
   洗浄washed with water

実験手順

1.94 g of 3-amino-2-chloro-6-methylphenol hydrochloride are added to 2.53 g of 2-[(4-aminophenyl)(ethyl)amino]ethanol hydrochloride in solution in 20 ml of water and 10 ml of ethanol. The pH is adjusted to 9.5 with 20% ammonium hydroxide in water. 36 ml of 9% aqueous hydrogen peroxide solution are subsequently added and the reaction medium is stirred at ambient temperature for 4 h 30. The solid form is filtered off and washed with water; 2.44 g of 3-amino-2-chloro-4-({4-[ethyl(2-hydroxyethyl)amino]phenyl}imino)-6-methylcyclohexa-2,5-dien-1-one (1k) are obtained.

出典