反応 #74708

反応方程式

phosphonium

acetic acid

aniline

→

acetanilide

収率 20.0%

反応条件

後処理

1. 1
   workup.ADDITIONwas added
2. 2
   workup.ADDITIONa mixture of 3.0 g
3. 3
   温度under reflux for 2 hours

実験手順

To the same reaction mixture containing the phosphonium salt as in Example 1 was added a mixture of 3.0 g. (0.05 mole) of acetic acid and 5.2 g. (0.056 mole) of aniline, and the resulting mixture was reacted under reflux for 2 hours. Thereafter, the same aftertreatment as in Example 1 was effected to obtain acetanilide, yield 20% based on acetic acid.

出典