反応 #742248

反応方程式

(E)-3-(2-hydroxy-phenyl)-2-methyl-acrylic acid

citronellol

p-toluene-sulfonic acid

water

→

colourless oil

(E)-3-(2-Hydroxy-phenyl)-2-methyl-acrylic acid 3,7 dimethyl-oct-6-enyl ester

溶媒

cyclohexane

hexane

反応条件

後処理

1. 1
   温度Then the reaction mixture was cooled down
2. 2
   洗浄washed
3. 3
   その他The organic phase was dried
4. 4
   ろ過filtered
5. 5
   その他evaporated to dryness
6. 6
   その他The resulting yellow oil was purified by chromatography

実験手順

A solution of 6 0 g of (E)-3-(2-hydroxy-phenyl)-2-methyl-acrylic acid, 5.3 g of citronellol and 1 g of p-toluene-sulfonic acid in 150 ml of cyclohexane was refluxed for 6.5 hours using a water separator. Then the reaction mixture was cooled down, diluted with hexane and washed to neutrality with saturated sodium bicarbonate and water. The organic phase was dried, filtered and evaporated to dryness. The resulting yellow oil was purified by chromatography to yield 6.45 g of a colourless oil.

出典