反応 #736802

反応方程式

Tertiary butylamine

glyphosate

N-t-butyl-N-phosphonomethylglycine

→

N-t-butylglycine

反応条件

実験手順

Gaertner, U.S. Pat. No. 3,927,080, describes the production of glyphosate by the acid hydrolysis of N-t-butyl-N-phosphonomethylglycine or its esters. Tertiary butylamine is reacted with a bromoacetate ester to produce an ester of N-t-butylglycine which is in turn reacted with formaldehyde and phosphorous acid to produce the N-t-butyl-N-phosphonomethylglycine precursor.

出典