反応 #736792

反応方程式

6-bromo-1-cyano-3-methyl-3H-dibenz[f,ij]isoquinoline-2,7-dione

p-aminophenylethanol

potassium acetate

HCl

→

1-Cyano-6-[4-(2-Hydroxyethyl)Anilino]-3-Methyl-3H-Dibenzo[f,ij]Isoquinoline-2,7-Dione

溶媒

acetone

butanol

反応条件

後処理

1. 1
   ろ過The solid product was collected by filtration
2. 2
   洗浄washed with water
3. 3
   その他dried in air
4. 4
   その他recrystallized twice from nitrobenzene
5. 5
   その他to remove a red impurity and traces of starting material
6. 6
   その他was obtained

実験手順

A mixture of 6-bromo-1-cyano-3-methyl-3H-dibenz[f,ij]isoquinoline-2,7-dione (2.0 g), p-aminophenylethanol (15 g), potassium acetate (2.0 g), a trace of cupric acetate, and butanol (10 ml) was heated gradually to about 80° C., held for 5-10 minutes, and then drained into 250 ml of 10% HCl. The solid product was collected by filtration, washed with water, dried in air, and recrystallized twice from nitrobenzene to remove a red impurity and traces of starting material. A yield of 0.65 g of product, which had a visible absorption maximum at 587 nm in acetone, was obtained, thus imparting a reddish-blue color to acetone. The structure is as follows: ##STR6##

出典