反応 #72533

反応方程式

trichloroacetyl chloride

pyrrole

potassium carbonate

→

title product

2,2,2-Trichloro-1-(1H-pyrrol-2-yl)ethanone

溶媒

ethyl ether

water

ethyl ether

反応条件

後処理

1. 1
   その他The phases are separated
2. 2
   乾燥the organic phase is dried over sodium sulphate
3. 3
   ろ過filtered
4. 4
   workup.ADDITIONActive carbon is added to this organic phase
5. 5
   workup.STIRRINGAfter stirring for 5 minutes
6. 6
   ろ過the organic phase is filtered
7. 7
   その他evaporated to dryness

実験手順

To a solution of trichloroacetyl chloride (160.7 mmoles) in ethyl ether (26 ml) there is added, dropwise over a period of 3 hours, a solution of pyrrole (149 mmoles) in ethyl ether (83 ml). After stirring for a further hour, a solution of potassium carbonate (94 mmoles) in water (39 ml) is added dropwise. The phases are separated and the organic phase is dried over sodium sulphate and filtered. Active carbon is added to this organic phase. After stirring for 5 minutes, the organic phase is filtered and evaporated to dryness to yield the title product.

出典