反応 #710461
ord-e4ad890d40d44f70a28960b2754401a0
反応方程式
2-amino-3-methyl 5-bromobenzoic acid methyl ester
N,N-diethyl ethylenediamine
→
N-diethylaminoethyl-2-amino-3-methyl-5-bromobenzamide
収率 84.2%
溶媒
反応条件
温度
78°CELSIUS
詳細条件
See reaction.notes.procedure_details.
後処理
- 1その他reacted for 4 hours
実験手順
To a 100 mL round-bottom flask, 0.1 mol of 2-amino-3-methyl 5-bromobenzoic acid methyl ester having the structural formula of VIII-2, 100 mL of ethanol, 0.3 mol of N,N-diethyl ethylenediamine were added, heated to 78° C. and reacted for 4 hours, after treatment 27.5 grams of N-diethylaminoethyl-2-amino-3-methyl-5-bromobenzamide having a structural formula of III-2 was obtained, and the yield was 84.2%;