反応 #7039

反応方程式

7-azaindole

butyraldehyde

→

1,1-di-(7-azaindol-3-yl)-butane

収率 15.0%

反応条件

後処理

1. 1
   その他ST 1436 was prepared
2. 2
   その他The reaction
3. 3
   温度however, was heated
4. 4
   温度under reflux for 48 hours
5. 5
   その他The end product was isolated
6. 6
   その他purified chromatographically on a silica column
7. 7
   洗浄eluting with a CH2Cl2

実験手順

ST 1436 was prepared as described in example 2/2 from 7-azaindole and butyraldehyde. The reaction, however, was heated under reflux for 48 hours. The end product was isolated and purified chromatographically on a silica column eluting with a CH2Cl2:CH3COCH3 gradient ranging from 9:1 to 4:6. Yield 15%.

出典