反応 #696695

反応方程式

1,4-diaminobutane

triethylamine

2-chloro-2-methyl-3-nitrosopentane

→

2-(4-aminobutyl)amino-2-methyl-3-pentanone oxime

溶媒

acetonitrile

acetonitrile

反応条件

後処理

1. 1
   その他to precipitate
2. 2
   workup.STIRRINGThe reaction mixture was stirred overnight
3. 3
   ろ過the product was filtered off
4. 4
   その他dried in vacuo
5. 5
   その他to give a white powder, (0.5 g; 86%)

実験手順

To a stirred solution of 1,4-diaminobutane (0.26 g; 2.9 mmol) and triethylamine (0.33 g; 3.2 mmol) in acetonitrile (5 ml) was added a solution of 2-chloro-2-methyl-3-nitrosopentane (0.485 g; 3.24 mmol) in acetonitrile (5 ml). After stirring for ca 10 minutes the product began to precipitate. The reaction mixture was stirred overnight and the product was filtered off and dried in vacuo to give a white powder, (0.5 g; 86%).

出典