反応 #69477

反応方程式

Methyl 8-[(2R)-(1-(3-methoxyphenyl)pyrrolidin-2-yl)]-2-morpholino-4-oxo-4H-chromene-6-carboxylate

sodium hydroxide

→

8-[(2R)-(1-(3-methoxyphenyl)pyrrolidin-2-yl)]-2-morpholino-4-oxo-4H-chromene-6-carboxylic acid

収率 74.8%

反応条件

実験手順

Methyl 8-[(2R)-(1-(3-methoxyphenyl)pyrrolidin-2-yl)]-2-morpholino-4-oxo-4H-chromene-6-carboxylate (90 mg, 0.19 mmol) was reacted with sodium hydroxide (38.7 mg, 0.97 mmol) to give 8-[(2R)-(1-(3-methoxyphenyl)pyrrolidin-2-yl)]-2-morpholino-4-oxo-4H-chromene-6-carboxylic acid (64 mg, 73%) as a beige solid. Mass Spectrum: m/z [M+H]+=451.

出典