反応 #691937

反応方程式

pentafluorobenzenesulfonyl chloride

ammonium chloride

sodium hydroxide

→

pentafluorobenzenesulfonamide

収率 36.0%

溶媒

acetone

反応条件

後処理

1. 1
   ろ過The precipitated product was filtered
2. 2
   その他recrystallized from toluene

実験手順

Under room temperature, a solution of 468 g of pentafluorobenzenesulfonyl chloride in acetone was added dropwise to an aqueous solution containing 964 g of ammonium chloride, during which a pH was adjusted to 7 with an aqueous sodium hydroxide solution. The precipitated product was filtered, and recrystallized from toluene to obtain 156 g of pentafluorobenzenesulfonamide as white crystals. A structure was confirmed by 1H-NMR, 19F-NMR and IR.

出典