反応 #6858

反応方程式

Benzyl chloroformate

6-methoxy-1-methyl-3,4-dihydroisoquinoline

triethylamine

→

6-methoxy-1-methylene-3,4-dihydro-1H-isoquinoline-2-carboxylic acid benzyl ester

溶媒

dichloromethane

反応条件

後処理

1. 1
   その他the volatile material was evaporated

実験手順

Benzyl chloroformate (0.30 mL) was added to an ice-cold solution of 6-methoxy-1-methyl-3,4-dihydroisoquinoline (0.36 g) and triethylamine (0.58 mL) in 10 mL dichloromethane. After 0.5 h, the volatile material was evaporated to furnish 0.66 g of 6-methoxy-1-methylene-3,4-dihydro-1H-isoquinoline-2-carboxylic acid benzyl ester.

出典