反応 #6853

反応方程式

propionyl chloride

3,4-dimethoxyphenylethylamine

3-methyl-4-methoxyphenylethylamine

(4-methoxy-phenyl)-ethylamine

acetic anhydride

→

1-ethyl-1,2,3,4-tetrahydro-isoquinolin-7-ol

1-Methyl-1,2,3,4-tetrahydro-isoquinoline-6,7-diol

1,6-dimethyl-1,2,3,4-tetrahydro-isoquinolin-7-ol

反応条件

実験手順

Similarly, 1-ethyl-1,2,3,4-tetrahydro-isoquinolin-7-ol was prepared by the above procedures by replacing the acetic anhydride in Procedure EEE with propionyl chloride. 1-Methyl-1,2,3,4-tetrahydro-isoquinoline-6,7-diol and 1,6-dimethyl-1,2,3,4-tetrahydro-isoquinolin-7-ol were prepared by replacing the (4-methoxy-phenyl)-ethylamine in procedure EEE with 3,4-dimethoxyphenylethylamine and 3-methyl-4-methoxyphenylethylamine, respectively.

出典