反応 #684990

反応方程式

hydrogen chloride

1-(3-(2-(1-benzothiophene-6-yl)ethoxy)propyl)-3-azetidinol

→

light yellow oil

1-(3-(2-(1-benzothiophene-6-yl)ethoxy)propyl)-3-azetidinol hydrochloride

溶媒

ethyl acetate

ethyl acetate

反応条件

後処理

1. 1
   workup.ADDITIONwas added to the obtained solution
2. 2
   workup.DISTILLATIONSubsequently, the solvent was distilled away under a reduced pressure

実験手順

0.28 g of 1-(3-(2-(1-benzothiophene-6-yl)ethoxy)propyl)-3-azetidinol was dissolved in 3.0 ml of ethyl acetate. Thereafter, 0.35 ml of an ethyl acetate solution containing 3.25 mol/l dry hydrogen chloride was added to the obtained solution, and the obtained mixture was stirred at a room temperature for 1 hour. Subsequently, the solvent was distilled away under a reduced pressure, so as to obtain 0.30 g of a light yellow oil product, 1-(3-(2-(1-benzothiophene-6-yl)ethoxy)propyl)-3-azetidinol hydrochloride.

出典