反応 #68421

反応方程式

2-isopropyl-6-methoxy-1H-indole-3-carbaldehyde

Compound 137

2-isopropyl-6-methoxy-1H-indole-3-carbaldehyde

3-(bromomethyl)pyridine

cyclobutyl bromide

HBr

3,4-difluorobenzylamine

→

title compound

6-Cyclobutoxy-N-(3,4-difluorobenzyl)-2-isopropyl-1-(pyridin-3-ylmethyl)-1H-indole-3-carboxamide

反応条件

実験手順

The title compound was prepared from 2-isopropyl-6-methoxy-1H-indole-3-carbaldehyde (Compound 137), 3-(bromomethyl)pyridine.HBr, 3,4-difluorobenzylamine, and cyclobutyl bromide by, in order, General Procedure J, General Procedure K, General Procedure C, General Procedure L, and General Procedure N.

出典