反応 #6827

反応方程式

Sodium hydroxide

4-formyl-benzoic acid methyl ester

nitromethane

→

4-(2-nitro-vinyl)-benzoic acid methyl ester

溶媒

methanol

反応条件

後処理

1. 1
   その他a precipitate was formed
2. 2
   その他The precipitate was isolated by filtration

実験手順

Sodium hydroxide (1 N, 2.3 mL) was added dropwise to 4-formyl-benzoic acid methyl ester (0.33 g) and nitromethane (0.11 ml) in 5 mL methanol at 0° C. The solution was acidified after 0.5 h and a precipitate was formed. The precipitate was isolated by filtration to give 228 mg of 4-(2-nitro-vinyl)-benzoic acid methyl ester.

出典