反応 #6814

反応方程式

cis-N-[4-(3-chlorophenyl)-but-3-enyl]-phthalimide

iodine

→

trans-N-[4-(3-chlorophenyl)-but-3-enyl]-phthalimide

収率 26.3%

溶媒

toluene

反応条件

後処理

1. 1
   その他The solvent was removed in vacuo
2. 2
   その他the residue was recrystallized from toluene/methanol

実験手順

A solution of cis-N-[4-(3-chlorophenyl)-but-3-enyl]-phthalimide (1.9 g) and iodine (50 mg) in 500 mL toluene was irradiated for 5 days with a 100-watt incandescent light bulb. The solvent was removed in vacuo and the residue was recrystallized from toluene/methanol to give 0.50 g of trans-N-[4-(3-chlorophenyl)-but-3-enyl]-phthalimide (no cis-isomer was observed by 1H-NMR).

出典