反応 #6808

反応方程式

oxalyl chloride

2,2-diphenylpropionic acid

→

2,2-Diphenylpropionic acid chloride

溶媒

dichloromethane

反応条件

後処理

1. 1
   workup.DISTILLATIONThe solvent is distilled off
2. 2
   その他the residue remaining is used in the next step without any further purification

実験手順

52.08 g (0.33 mol) of oxalyl chloride are slowly added dropwise at 20° C. to a suspension of 25.0 g (0.11 mol) of 2,2-diphenylpropionic acid, 100 mL of dichloromethane, and 4 drops of dimethylformamide. The mixture is stirred for 1 hour at 20° C. and 0.5 hour at 50° C. The solvent is distilled off and the residue remaining is used in the next step without any further purification.

出典