反応 #67682

反応方程式

2-methyl-1-phenylpropan-2-yl 2-((4R,6S)-6-(chloromethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate

sodium 1-methyl-1H-benzo[d]imidazole-2-thiolate

Sodium 1-methyl-1H-benzo[d]imidazole-2-thiolate

→

title compound

2-methyl-1-phenylpropan-2-yl 2-((4R,6S)-2,2-dimethyl-6-((1-methyl-1H-benzo[d]imidazol-2-ylthio)methyl)-1,3-dioxan-4-yl)acetate

反応条件

実験手順

The procedure was carried out in the same manner as in Example 11, except that 3.5 g of 2-methyl-1-phenylpropan-2-yl 2-((4R,6S)-6-(chloromethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate was used in place of 30 g thereof, and sodium 1-methyl-1H-benzo[d]imidazole-2-thiolate (3.7 g) prepared in Example 9 was used in place of sodium 1-phenyl-1H-tetrazole-5-thiolate. The title compound was obtained (4.7 g).

出典