反応 #674321

反応方程式

2-(3-aminophenyl)ethanesulfonamide

2-(3-Aminophenyl)ethanesulfonamide

A1

3-[(4-Chloro-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide

2,4-dichloro-1,3,5-triazine

→

A4

2-[3-((4-Chloro-1,3,5-triazin-2-yl)amino)phenyl]ethanesulfonamide

反応条件

後処理

1. 1
   その他The crude product was purified by flash chromatography on silica gel (DCM/MeOH=100:0 to 4:1)

実験手順

A4 was prepared following the general procedure reported for A1 using 2,4-dichloro-1,3,5-triazine and 2-(3-aminophenyl)ethanesulfonamide A3 as reacting agents. The crude product was purified by flash chromatography on silica gel (DCM/MeOH=100:0 to 4:1) to yield the desired product A5 (54%, 65% purity) as a brown solid. MS (ES) C11H12ClN5O2S requires: 313. found: 314 (M+H)+.

出典