反応 #67394

反応方程式

3,3′,5,5′-tetrakis(dibromoethyl)-1,1′-biadamantane

potassium tert-butoxide

water

→

3,3′,5,5′-tetraethynyl-1,1′-biadamantane

溶媒

dimethyl sulfoxide

反応条件

後処理

1. 1
   抽出the mixture was extracted 3 times
2. 2
   洗浄washed with 200 ml of water
3. 3
   乾燥dried over magnesium sulfate
4. 4
   濃縮the organic layer was concentrated

実験手順

The obtained 3,3′,5,5′-tetrakis(dibromoethyl)-1,1′-biadamantane was dissolved in 200 ml of dimethyl sulfoxide, and then 28 g (250 mmol) of potassium tert-butoxide was added at room temperature and the mixture was stirred for 48 hours. The reaction mixture was added to 400 ml of water, the mixture was extracted 3 times using 200 ml of dichloromethane each time and then washed with 200 ml of water and dried over magnesium sulfate, and the organic layer was concentrated to obtain 11.0 g of 3,3′,5,5′-tetraethynyl-1,1′-biadamantane.

出典