反応 #673737

反応方程式

5-chloro-2-methyl-phenyl isothiocyanate

4-methyl-2-amino-oxazole

→

title compound

収率 54.1%

1-(5-Chloro-2-methyl-phenyl)-3-(4-methyl-oxazol-2-yl)-thiourea

収率 54.1%

反応条件

後処理

1. 1
   その他Prepared

実験手順

Prepared using Method A from 10.0 g (54.5 mmol) of 5-chloro-2-methyl-phenyl isothiocyanate and 5.39 g (55 mmol) of 4-methyl-2-amino-oxazole to give 8.3 g of title compound as a yellow solid, m.p. 207-208° C. An additional crop (4.8 g, m.p. 207-208° C.) was obtained from the mother liquor (86% combined yield).

出典