反応 #67266

反応方程式

5-bromo-2-[(2S)-oxiran-2-ylmethoxy]benzaldehyde

m-CPBA

→

5-BROMO-2-[(2S)-OXIRAN-2-YLMETHOXY]PHENYL FORMATE

溶媒

DCM

反応条件

後処理

1. 1
   その他Preparation
2. 2
   温度The mixture was heated
3. 3
   温度at reflux for 3 h

実験手順

Preparation according to Preparation 2 using 5-bromo-2-[(2S)-oxiran-2-ylmethoxy]benzaldehyde (8.3 g, 32 mmol), DCM (100 ml) and m-CPBA (77%, 10.9 g, 48.6 mmol). The mixture was heated at reflux for 3 h. Crude yield: 8.5 g. MS m/z (rel. intensity, 70 eV) 274 (M+, 10), 273 (M+, 9), 189 (98), 188 (bp), 57 (77).

出典