反応 #67245

ord-115a309523ce46fd8dc9390864734267

反応方程式

Cc1ccc(S(=O)(=O)OCC2CCc3ccc(S(C)(=O)=O)cc3O2)cc1
[7-(methylsulfonyl)-3,4-dihydro-2H-chromen-2-yl]methyl 4-methylbenzenesulfonate
CCCNCCC
N-propylpropan-1-amine
→
CCCN(CCC)CC1CCc2ccc(S(C)(=O)=O)cc2O1
N-{[7-(METHYLSULFONYL)-3,4-DIHYDRO-2H-CHROMEN-2-YL]METHYL}-N-PROPYLPROPAN-1-AMINE

反応物

Cc1ccc(S(=O)(=O)OCC2CCc3ccc(S(C)(=O)=O)cc3O2)cc1
[7-(methylsulfonyl)-3,4-dihydro-2H-chromen-2-yl]methyl 4-methylbenzenesulfonate
—
( 10 )
—
( 7 )
—
( 4 )
—
( 6 )
CCCNCCC
N-propylpropan-1-amine

試薬

なし

溶媒

CC#N
ACN

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他Preparation

実験手順

Preparation according to Example 25: [7-(methylsulfonyl)-3,4-dihydro-2H-chromen-2-yl]methyl 4-methylbenzenesulfonate (0.020 g, 0.0504 mmol), N-propylpropan-1-amine (0.5 ml), ACN (3 ml). MS m/z (rel. intensity, 70 eV) 325 (M+, 1), 296 (7), 131 (4), 115 (10), 114 (bp), 86 (6).

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US08524766B2uspto-grants-2013_09