反応 #67194

ord-e4bed67b92f94c12a8a588779093e7fe

反応方程式

Cc1ccc(S(=O)(=O)OCC2COc3ccc(S(C)(=O)=O)cc3O2)cc1
[7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl 4-methylbenzenesulfonate
CCCCN
butan-1-amine
→
CCCCNCC1COc2ccc(S(C)(=O)=O)cc2O1
N-{[7-(METHYLSULFONYL)-2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL]METHYL}BUTAN-1-AMINE

反応物

—
( 6 )
Cc1ccc(S(=O)(=O)OCC2COc3ccc(S(C)(=O)=O)cc3O2)cc1
[7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl 4-methylbenzenesulfonate
CCCCN
butan-1-amine
—
( 5 )
—
( 5 )

試薬

なし

溶媒

CC#N
ACN

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他Preparation

実験手順

Preparation according to Example 25 using [7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl 4-methylbenzenesulfonate (0.018 g, 0.046 mmol), butan-1-amine (0.5 ml), ACN (3 ml). MS m/z (rel. intensity, 70 eV) 299 (M+, 6), 256 (5), 87 (6), 86 (bp), 70 (5).

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US08524766B2uspto-grants-2013_09