反応 #66838

反応方程式

tert-butyl 4-chloro-7,8-dihydropyrido[3′,4′:4,5]thieno[2,3-d]pyrimidine-6(5H)-carboxylate

tert-Butyl 4-chloro-7,8-dihydropyrido[3′,4′:4,5]thieno[2,3-d]pyrimidine-6(5H)-carboxylate

3,4-dichloroaniline

→

title compound

N-(3,4-Dichlorophenyl)-5,6,7,8-tetrahydropyrido[3′,4′:4,5]thieno[2,3-d]pyrimidin-4-amine

反応条件

後処理

1. 1
   その他to yield 127 mg (91%)

実験手順

The title compound was prepared in analogy to Example 12A from tert-butyl 4-chloro-7,8-dihydropyrido[3′,4′:4,5]thieno[2,3-d]pyrimidine-6(5H)-carboxylate from Example 75A (122 mg, 0.37 mmol) and 3,4-dichloroaniline (64 mg, 0.39 mmol) to yield 127 mg (91%).

出典