反応 #667932

反応方程式

1-methyl-2,3-difluorobenzene

1-methyl-3-chloro-4-fluorobenzene

1-methyl-3,4-difluorobenzene

1-(2-propenyl)-2-chloro-2,3,3-trifluorocyclobutane

1-methyl-1-vinyl-2-chloro-2,3,3-trifluorocyclobutane

→

1-methyl-2-chloro-3-fluorobenzene

収率 88.0%

反応条件

後処理

1. 1
   その他At 400° C.

実験手順

The general procedure was followed using a mixture of 1-(2-propenyl)-2-chloro-2,3,3-trifluorocyclobutane and 1-methyl-1-vinyl-2-chloro-2,3,3-trifluorocyclobutane as the liquid feed at a flow rate of 1 ml/hr. Nitrogen gas was used as the inert carrier. The reactor was charged with 3 g of AL-0104 (tableted activated alumina containing 99% Al2O3). At 400° C. the yield of the produced aromatic products was 12% combined yield of 1-methyl-2,3-difluorobenzene and 1-methyl-3,4-difluorobenzene and a combined yield of 88% of 1-methyl-2-chloro-3-fluorobenzene and 1-methyl-3-chloro-4-fluorobenzene.

出典