反応 #6667

反応方程式

1-decanol

sodium methylate

→

sodium decylate

溶媒

methanol

反応条件

後処理

1. 1
   温度heated under reduced pressure
2. 2
   workup.DISTILLATIONto distill off methanol
3. 3
   workup.ADDITIONInto a 1 l four-necked flask, N,N-dimethylformamide (150 ml) and CH3CHClCOO(CH2)9CH3 (27.1 g) obtained in Example 19 were charged
4. 4
   workup.STIRRINGstirred

実験手順

Into a 500 ml eggplant type flask, 1-decanol (180 g) and a methanol solution of sodium methylate (28%) were charged, stirred and heated under reduced pressure to distill off methanol. By GC, it was confirmed that no methanol remained in the reaction solution. Into a 1 l four-necked flask, N,N-dimethylformamide (150 ml) and CH3CHClCOO(CH2)9CH3 (27.1 g) obtained in Example 19 were charged and stirred, and a solution of sodium decylate obtained in the above operation was added dropwise at an internal temperature of not higher than 25° C. The mixture was heated to an internal temperature of 70° C. and stirred for 30 minutes.

出典