反応 #66590

反応方程式

Iodomethane

3-((dimethylamino)methyl)-5-methylhexan-2-one

→

title product

収率 68.4%

(2-Acetyl-4-methyl-pentyl)-trimethyl-ammonium iodide

収率 68.4%

溶媒

ethyl acetate

反応条件

後処理

1. 1
   ろ過, and the resulting preciptant was collected by filtration

実験手順

Iodomethane (20 g, 140.94 mmol, 2.00 equiv) was added dropwise to a solution of 3-((dimethylamino)methyl)-5-methylhexan-2-one (12 g, 70.05 mmol, 1.00 equiv) and ethyl acetate (50 mL). The solution was stirred at ambient temperature for about 16 hours., and the resulting preciptant was collected by filtration to afford the title product (15 g, yield=68%).

出典