反応 #66435
ord-cda3a113e7984ffbbcb9d5012335d664
反応条件
詳細条件
See reaction.notes.procedure_details.
後処理
- 1洗浄washed with aq. NaOH and brine
- 2濃縮concentrated in vacuo
実験手順
To a chilled suspension of 3-aminobenzyl alcohol (9.24 g, 75 mmol) in THF (50 mL) was added neat acetic anhydride (8.1 mL, 86 mmol). The reaction mixture was stirred cold for 1 hr, diluted with EtOAc, washed with aq. NaOH and brine, and concentrated in vacuo to give N-[3-(hydroxymethyl)phenyl]acetamide (10.5 g, 85%).