反応 #66413

反応方程式

2-(4-amino-2-methylphenyl)-5-chlorobenzo[c]azoline-1,3-dione

thiophosgene

→

desired product

収率 148.1%

4-(5-chloro-1,3-dioxobenzo[c]azolidin-2-yl)-3-methylbenzenisothiocyanate

収率 148.1%

溶媒

acetone

反応条件

後処理

1. 1
   workup.DISSOLUTIONThe yellow slurry dissolved whereupon a white precipitate
2. 2
   その他formed
3. 3
   ろ過this solid was collected by filtration
4. 4
   その他dried

実験手順

To a slurry of 150 mg (0.52 mmol) of 2-(4-amino-2-methylphenyl)-5-chlorobenzo[c]azoline-1,3-dione in 2 mL of acetone, was added 41 uL (0.54 mmol) of thiophosgene. The yellow slurry dissolved whereupon a white precipitate formed. After 1 h, this solid was collected by filtration and dried to give 127 mg (74%) of the desired product.

出典