反応 #661287

反応方程式

1b

3-[(3-Amino-4-methylamino-benzoyl)-phenyl-amino]-propionic acid methyl ester

N-(4-cyano-phenyl)-glycine

CDI

→

3-({3-[2-(4-Cyano-phenylamino)-acetylamino]-4-methylamino-benzoyl}-phenyl-amino)-propionic acid methyl ester

溶媒

THF

反応条件

後処理

1. 1
   その他After completion of the reaction the mixture
2. 2
   その他was evaporated to dryness
3. 3
   その他the crude product was used without further purification

実験手順

The product of 1b (23.2 mmol) and N-(4-cyano-phenyl)-glycine (23.2 mmol) were coupled with CDI (23.2 mmol) in dry THF at room temperature. After completion of the reaction the mixture was evaporated to dryness and the crude product was used without further purification.

出典