反応 #6610

反応方程式

water

4-carboxybenzyl 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl ether

potassium carbonate

iodoethane

→

title compound

収率 40.9%

4-Carbethoxybenzyl 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl ether

収率 40.9%

溶媒

butanone

反応条件

後処理

1. 1
   抽出extracted with ether
2. 2
   洗浄the organic phase was washed with water
3. 3
   乾燥dried over Na2SO4
4. 4
   濃縮concentrated
5. 5
   その他Recrystallization from methanol

実験手順

2 g (6 mmol) of 4-carboxybenzyl 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl ether, 2.7 g (19.6 mmol) of anhydrous potassium carbonate and 19 g (12.4 mmol) of iodoethane in 18 ml of butanone were refluxed for 7 h. The mixture was then poured into water and extracted with ether, and the organic phase was washed with water, dried over Na2SO4 and concentrated. Recrystallization from methanol resulted in 0.9 g of the title compound of melting point 76°-77° C.

出典