反応 #6605

反応方程式

5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthol

4-cyanobenzyl chloride

potassium carbonate

water

→

title compound

収率 98.6%

4-Cyanobenzyl 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl ether

収率 98.6%

溶媒

butanone

dimethylformamide

反応条件

後処理

1. 1
   温度The mixture was cooled
2. 2
   ろ過the solid was filtered off with suction
3. 3
   洗浄washed with water
4. 4
   その他Drying

実験手順

40.8 g (0.2 mol) of 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthol, 30.4 g (0.2 mol) of 4-cyanobenzyl chloride and 80 g (1.2 mol) of anhydrous potassium carbonate in 400 ml of butanone and 300 ml of dimethylformamide were refluxed for 9 h. The mixture was cooled and then poured into 1.5 l of water, and the solid was filtered off with suction and washed with water. Drying resulted in 63 g of the title compound of melting point 149°-150° C.

出典