反応 #65962
ord-845bb11cfab64d898e0390f7ee4a116c
反応方程式
1-naphthol
formalin
piperidine
morpholine
→
2-(piperidinomethyl)-1-naphthol
2-(morpholinomethyl)-1-naphthol
反応条件
詳細条件
See reaction.notes.procedure_details.
実験手順
Anon. (USA) (Res. Discl., 236, 380 (Ger), 1983) discloses a Mannich reaction of 1-naphthol with formalin and piperidine or morpholine to yield 2-(piperidinomethyl)-1-naphthol or 2-(morpholinomethyl)-1-naphthol, respectively. These compounds were subjected to hydrogenolysis (Pd/C) whereby 2-methyl-1-naphthol was produced