反応 #65870

反応方程式

2,2-difluoro-1,3-benzodioxole

N,N,N',N'-tetramethylethylenediamine

n-butyllithium

→

title compound

2,2-difluoro-1,3-benzodioxol-4-yl-lithium

溶媒

toluene

n-butane

反応条件

後処理

1. 1
   その他The resulting reaction mixture

実験手順

39.3 g (339 mmol) of N,N,N',N'-tetramethylethylenediamine are added dropwise under a nitrogen atmosphere at from -15° to -10° C. to 137.8 g (409 mmol) of n-butyllithium solution (19.0% in toluene). The resulting reaction mixture is added dropwise at from -15° to -10° C. under a nitrogen atmosphere to a solution of 53.3 g (337 mmol) of 2,2-difluoro-1,3-benzodioxole in 46 ml of toluene, n-butane being formed in addition to the title compound.

出典