反応 #65846

反応方程式

2,3-dihydroxypyridine

2,3-dichloro-1,1,1,4,4,4-hexafluorobut-2-ene

→

2-(1-Chloro-2,2,2-trifluoroethyl)-2-trifluoromethyl-[1,3]-dioxolo[4,5-b]pyridine

反応条件

後処理

1. 1
   workup.DISTILLATIONAfter distillation under high vacuum
2. 2
   その他the product was obtained in an amount of 15.5 g (=50% of theory) in the form of colourless crystals

実験手順

11 g of 2,3-dihydroxypyridine were reacted with 23.5 g of 2,3-dichloro-1,1,1,4,4,4-hexafluorobut-2-ene as described in Example 2. After distillation under high vacuum, the product was obtained in an amount of 15.5 g (=50% of theory) in the form of colourless crystals. The NMR spectra showed the following characteristic absorptions: 19F NMR: -68.5 and -81.6 ppm. 1H NMR: 4.81 ppm.

出典