反応 #657258

反応方程式

ethyl-1-tritylpyrazole-4-carboxylate

dimethyl-3,5-pyrazoledicarboxylate

sodium hydride

trityl chloride

→

Dimethyl 1-trityl-3,5-pyrazoledicarboxylate

収率 98.0%

溶媒

dimethylformamide

反応条件

後処理

1. 1
   その他has been isolated

実験手順

This compound is a white microcrystalline solid that has been isolated following the methodology described in 2b for ethyl-1-tritylpyrazole-4-carboxylate, by reaction of with dimethyl-3,5-pyrazoledicarboxylate (1.411 g, 7.66 mmol) with sodium hydride (250 mg, 10.41 mmol) in dry dimethylformamide (20 mL), followed by treatment with trityl chloride (2.135 g, 7.66 mmol). Yield: 98% (3.200 g, 7.50 mmol).

出典