反応 #657256

反応方程式

sodium hydride

3,5-dimethyl-4-methoxyethyl-1-tritylpyrazole

1-trityl-4-methoxymethylpyrazole

iodoethane

1-trityl-4-hydroxymethylpyrazole

→

1-trityl-4-ethoxymethylpyrazole

収率 87.0%

反応条件

後処理

1. 1
   その他has been obtained

実験手順

This compound is a slightly yellow solid and has been obtained as described in 2b for 1-trityl-4-methoxymethylpyrazole, starting from 1-trityl-4-hydroxymethylpyrazole (1.250 g; 3.67 mmol), sodium hydride (221 mg; 5.51 mmol) and iodoethane (1.5 mL; 18.35 mmol), as described in example 2a for 3,5-dimethyl-4-methoxyethyl-1-tritylpyrazole. Yield: 87% (1.174 g, 3.19 mmol).

出典