反応 #656979

反応方程式

hydrogen

methyl 6-[1-(3-pyridyl)ethenyl]-2-naphthoate

→

methyl 6-[1-(3-pyridyl)ethyl]-2-naphthoate

収率 20.0%

溶媒

methanol

反応条件

後処理

1. 1
   その他The catalyst is then removed by filtration
2. 2
   その他the solution is evaporated
3. 3
   その他chromatographed on silica gel

実験手順

130 mg of Pd/C (10%) are added to 0.25 g (0.86 mmol) of methyl 6-[1-(3-pyridyl)ethenyl]-2-naphthoate in 25 ml of absolute methanol, and hydrogenation is carried out under atmospheric pressure (hydrogen uptake: 40 ml). The catalyst is then removed by filtration, and the solution is evaporated and chromatographed on silica gel using ethyl acetate. 50 mg (20%) of methyl 6-[1-(3-pyridyl)ethyl]-2-naphthoate are obtained as an oil. RF (ethyl acetate): 0.34.

出典