反応 #65680

反応方程式

3-bromophenol

ethyl acrylate

→

ethyl 3-(m-bromophenoxy)propionate

収率 52.9%

溶媒

methanol

反応条件

後処理

1. 1
   温度at reflux overnight
2. 2
   workup.DISTILLATIONAfter distilling off the excess acrylate at normal pressure
3. 3
   workup.DISTILLATIONthe residue was distilled in a high vacuum

実験手順

A mixture of 20 g of 3-bromophenol, 92 g of ethyl acrylate and 1.8 ml of Triton B (35% in methanol) was boiled at reflux overnight. After distilling off the excess acrylate at normal pressure, the residue was distilled in a high vacuum. There were obtained 16.7 g of ethyl 3-(m-bromophenoxy)propionate as a colorless oil, boiling point 107°-110° C./67 Pa.

出典