反応 #65493

反応方程式

product

1-(4-bromophenyl) 2-heptyn-1-one

1-amino 2-methylpyridinium 2,4,6-trimethyl-benzene sulfonate

potassium carbonate

→

(4-bromophenyl) (2-butyl 7-methyl pyrazolo(1,5-a) pyridin-3-yl) methanone

溶媒

dimethylformamide

反応条件

実験手順

A mixture of 11.4 g of the product of Stage A of Example 1, 250 ml of dimethylformamide and 9.81 g of 1-amino 2-methylpyridinium 2,4,6-trimethyl-benzene sulfonate (Synthesis, 1977, page 1, TAMURA, et al.) and 5.11 g of potassium carbonate were stirred for 5 hours at ambient temperature.

出典