反応 #652474

ord-f29a556ee6b14e0cb9dcb292ad434e36

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

2-[4-(2-Diethylamino-ethoxy)-benzyl]-2-(4-methoxy-benzenesulfonyl)-hexanoic acid was prepared starting from 2-[4-(2-diethylamino-ethoxy)-benzyl]-2-(4-methoxy-benzenesulfonyl)-hexanoic acid ethyl ester (8 g, 15.4 mmol) dissolved in methanol (200 ml) and 10 N NaOH (30 ml). The resulting mixture was worked up as outlined in example 1. Yield 3.88 g crude (51%); brown oil; MS: 492 (M+H)+.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US06172057B2uspto-grants-2001_01