反応 #65210

反応方程式

5-hydroxyindan

triethylamine

2-methylbenzoyl chloride

→

5-(2-methylbenzoyloxy)indan

溶媒

dichloromethane

反応条件

後処理

1. 1
   温度cooling for one hour
2. 2
   洗浄after which it was washed with water
3. 3
   乾燥dried (MgSO4)
4. 4
   workup.DISTILLATIONThe solvent was then distilled off

実験手順

To an ice-cooled mixture of 5-hydroxyindan (13.4 g), triethylamine (14.0 ml) and dichloromethane (150 ml) was added 2-methylbenzoyl chloride (15.4 ml) dropwise with constant stirring. The mixture was further stirred under ice-cooling for one hour, after which it was washed with water and dried (MgSO4). The solvent was then distilled off to give 5-(2-methylbenzoyloxy)indan as oil in quantitative yield.

出典