反応 #651863

ord-a1275bfe1189467a85a0e45ec835f1ea

反応方程式

CCCCCCCCOc1ccc2c(c1)cc(F)c1cc(Br)ccc12
7-bromo-9-fluoro-2-octyloxyphenanthrene
CCCCCCOc1ccc(B(O)O)cn1
6-hexyloxypyridine-3-boronic acid
O=C([O-])[O-].[Na+].[Na+]
sodium carbonate
→
CCCCCCCCOc1ccc2c(c1)cc(F)c1cc(-c3ccc(OCCCCCC)nc3)ccc12
9-Fluoro-7-(6-hexyloxypyrid-3-yl)-2-octyloxyphenanthrene

反応物

CCCCCCCCOc1ccc2c(c1)cc(F)c1cc(Br)ccc12
7-bromo-9-fluoro-2-octyloxyphenanthrene
CCCCCCOc1ccc(B(O)O)cn1
6-hexyloxypyridine-3-boronic acid
O=C([O-])[O-].[Na+].[Na+]
sodium carbonate

試薬

c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1
tetrakis(triphenylphosphine)palladium(0)

溶媒

CCO.Cc1ccccc1.O
toluene ethanol H2O

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

From 7-bromo-9-fluoro-2-octyloxyphenanthrene by reaction with 6-hexyloxypyridine-3-boronic acid, sodium carbonate and tetrakis(triphenylphosphine)palladium(0) in toluene/ethanol/H2O.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US06168838Auspto-grants-2001_01