反応 #65060

反応方程式

Sodium cyanide

4-chlorobenzenediazonium tetrafluoroborate

→

4-Chlorobenzonitrile

収率 75.0%

溶媒

water

water

反応条件

後処理

1. 1
   workup.STIRRINGstirred until it
2. 2
   その他to react at room temperature
3. 3
   抽出The mixture was extracted by ethyl acetate
4. 4
   その他had been formed in 75% yield

実験手順

Sodium cyanide (2.94 g; 0.06 mol) was added to water and stirred. Cuprous cyanide (2.7 g; 0.03 mol) was added to the mixture stirred until it became homogeneous. 4-chlorobenzenediazonium tetrafluoroborate (5.66 g; 0.025 mol) in water (10 ml) was added to one portion. The mixture was allowed to react at room temperature. The mixture was extracted by ethyl acetate and the extract analysed by means of gas chromatography which indicated that 4-chlorobenzonitrile had been formed in 75% yield.

出典